Vitamin K

Anaphylactic shock due to vitamin K in a newborn and review of literature. 2014, Koklu, J Matern Fetal Neonatal Med

Infants are born with an immature system of congenital immunity, because their immune system is weaker than in adults, anaphylactic reaction develops less likely in them. The possible mechanism of the formation of anaphylaxis in newborns has not yet been clarified. the first case of anaphylactic shock due to the injection of vitamin K. More: [1]


Anaphylaxis following single component measles and rubella immunization. 2008, Erlewyn-Lajeunesse, Arch Dis Child

Safety of the MMR vaccine was discussed in detail in measles and mumps sections. Here are some more studies, focused more on rubella:

The risk of anaphylactic shock due to vaccination is 1.89 in 10,000 cases for measles vaccine and 2.24 in 10,000 cases for rubella vaccine. The authors believe that these figures are underestimated, since the exact number of administered vaccines is unknown, and that the actual figures may be 3-5 times higher.
The risk of anaphylactic shock due to MMR vaccine was estimated as 1.4 in 100,000 cases in 2004. However, in 2003 the risk of anaphylactic shock due to all the vaccines was estimated at 0.65 in a million.


The concept of allergies was unknown until 1906. It was invented by an Austrian pediatrician and used to describe the strange symptoms he observed in those who received the diphtheria immunoglobulin.
The concept of anaphylactic shock also did not exist until 1902.


Adverse events associated with childhood vaccines other than pertussis and rubella. 1994, Stratton, JAMA

An IOM report, in which, among other things, is stated that they have found a causal relationship between tetanus/diphtheria vaccine and Guillain-Barré syndrome, anaphylactic shock and brachial neuritis.