Effect of alternative aluminum adjuvants on the absorption and immunogenicity of HPV16 L1 VLPs in mice. 2007, Caulfield, Hum Vaccin

This articles compares the immune response to these new adjuvants with aluminum hydroxide on mice. The authors happily conclude that both of the new adjuvants induce an immune response 3-8 greater than the immune response to aluminum hydroxide. For some reason they never mention that eightfold immune response also means an eightfold risk of the autoimmune response.

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