The exact cause of Alzheimer’s disease is still unknown, but aluminum plays a major part in it.
Another meta-analysis on this topic.
Even though this article is mainly about the role of aluminum in the Alzheimer’s disease, it also lists the currently known mechanisms of aluminum’s influence on biological processes.
Despite the fact that aluminum is one of the most common metals on Earth, in nature it is found only in the compounds with silicon and oxygen. Men only learned how to produce pure aluminum and create aluminum salts in the late nineteenth century.
Aluminum has no useful biological function.
Aluminum is a strong neurotoxin, which inhibits more than 200 biological processes.
Among other things, aluminum binds with ATP (which causes chronic fatigue), changes DNA, kills nerve cells, destroys the homeostasis of useful minerals, such as magnesium, calcium and iron, by mimicking them, etc.
The closer the arteries are to the brain, the higher is the concentration of aluminum in patients with Alzheimer’s disease.
Patients with familial form of Alzheimer’s have been found to have incredibly high levels of aluminum in their brains.